許言

學術簡曆:

• 2021.7- beat365官方网站，特聘研究員，博士生導師， PI
• 2018-2021 加州理工學院，博士後 (合作導師：Prof. Robert H. Grubbs)
• 2013-2018 德州大學奧斯汀分校、芝加哥大學，博士 (導師：Prof. Guangbin Dong)
• 2009-2013beat365官方网站，本科學習（導師: 王劍波教授、張豔教授）

研究領域及興趣：

本課題組的主要研究方向是基于催化策略創新并輔以新試劑開發的有機合成方法學。其中我們尤為感興趣的内容包括針對常見化學結構開發非常見的連續或易位官能團化，新型碳氫及烯烴轉化，以及複雜骨架的修飾和結構調整。我們的研究涉及過渡金屬催化和光催化的前沿領域。 歡迎優秀學子報考博士研究生或參與本科生科研，同時面向國内外招聘博士後和研究助理，具體申請方式請見課題組主頁和化學院招聘信息。

代表性論文：

1. Wang, Y.; Zhang, Z.; Xu, Y.*, "cis-Selective Acyclic Diene Metathesis Polymerization Using Bulky Cyclometalated Ruthenium Carbene Catalysts", Macromolecules 2023, 56, 9138 – 9145.
2. Chen, K.†; Zeng, Q.†; Xie, L.; Xue, Z.; Wang, J.; Xu. Y.* “Functional-group translocation of cyano groups by reversible C–H sampling”, Nature 2023, 620, 1007–1012.
3. Xu, Y.; Qi, X.; Zheng, P.; Berti, C. C.; Liu, P.; Dong, G. “Deacylative Transformations of Ketones via Aromatization-Promoted C−C Bond Activation”, Nature, 2019, 567, 373–378.
4. Xu, Y.; Gan, Q.; Samkian, A. E.; Ko, J. H.; Grubbs, R. H. “Bulky Cyclometalated Ruthenium Nitrates for Challenging Z-Selective Metathesis: Efficient One-Step Access to α-Oxygenated Z-Olefins from Acrylates and Allyl Alcohols”, Angew. Chem. Int. Ed., 2022, 61, e202113089.
5. Zhou, X.; Xu. Y.*; Dong, G*. “Olefination via Cu-Mediated Dehydroacylation of Unstrained Ketones”, J. Am. Chem. Soc. 2021, 143, 20042–20048. (*co-corresponding)
6. Zhou, X.; Xu. Y.*; Dong, G*.“Deacylation-Aided C–H Alkylative Annulation through C–C Cleavage of Unstrained Ketones”, Nat. Catal., 2021,4,703-710. (*co-corresponding) 
7. Xu, Y.; Wong, J. J.; Samkian, A. E.; Ko, J. H.; Chen, S.; Houk, K. N.; Grubbs, R. H. “Efficient Z-Selective Olefin-Acrylamide Cross-Metathesis Enabled by Sterically Demanding Cyclometalated Ruthenium Catalysts”, J. Am. Chem. Soc., 2020, 142, 20987–20993. 
8. Xu, Y.; Dong, G. “sp3 C–H Activation via Exo-type Directing Groups”, Chem. Sci., 2018, 9, 1424–1432. 
9. Xu, Y.; Young, M. C.; Dong, G. “Catalytic Coupling between Unactivated Aliphatic C–H Bonds and Alkynes via a Metal–Hydride Pathway”, J. Am. Chem. Soc., 2017, 139, 5716–5719.
10. Xu, Y. †; Young, M. C. †; Wang, C.; Magness, D.; Dong, G. “Catalytic C(sp3)–H Arylation of Free Primary Amines with an exo Directing Group Generated In Situ”, Angew. Chem. Int. Ed., 2016, 55, 9084–9087.
11. Xu, Y.; Su, T.; Huang, Z.; Dong, G. “Practical Direct α-Arylation of Cyclopentanones by Palladium/Enamine Cooperative Catalysis”, Angew. Chem. Int. Ed., 2016, 55, 2559–2563.
12. Xu, Y. †; Yan, G. †; Ren, Z.; Dong, G. “Diverse sp3 C−H Functionalization through Alcohol β-Sulfonyloxylation", Nat. Chem., 2015, 7, 829-834. 
13. Samkian, A. E. †; Xu, Y. †; Virgil, S. C.; Yoon, K.-Y.; Grubbs, R. H. “Synthesis and Activity of Six-Membered Cyclic Alkyl Amino Carbene–Ruthenium Olefin Metathesis Catalysts”, Organometallics, 2020, 39, 495–499.