黃永棋

beat365 化學學院
2007級研究生 2012年7月畢業
去向：St. Jude Children's Research Hospital博士後，後任山東大學助理教授，再後任湖北工業大學副教授
研究方向：天然無序蛋白質在分子結合過程中的特性
Email:yqhuang_at_pku.edu.cn
English Version

 

簡曆:

2003年9月-2007年7月，山東大學化學與化工學院，理學學士

2007年9月-2012年7月，beat365官方网站，理學博士

2012年9月-2015年9月，美國St. Jude Children's Research Hospital，博士後

2016年1月-2016年9月，山東大學化學與化工學院，助理研究員

2016年9月-？？？，湖北工業大學，生物工程與食品學院，副教授

 

發表論文:

1. Huaiqing Cao, Yongqi Huang*, and Zhirong Liu*. Interplay between binding affinity and kinetics in protein-protein interactions. Proteins: Struct. Funct. Bioinform. 84 (7), 920-933 (2016).

2. Zhirong Liu and Yongqi Huang. Advantages of proteins being disordered. Protein. Sci. 23 (5), 539-550 (2014). (invited review)

3. Yongqi Huang and Zhirong Liu. Do intrinsically disordered proteins possess high specificity in protein–protein interactions? Chem. Eur. J. 19 (14), 4462-4467 (2013).

4. Zhirong Liu and Yongqi Huang. Evidences for the unfolding mechanism of three-dimensional domain swapping. Protein Sci. 22 (3), 280-286 (2013).

5. Yongqi Huang, Xue Kang, Bing Xia, and Zhirong Liu. Mechanism of 3D domain swapping for Mpro-C: clues from molecular simulations. Acta Phys. -Chim. Sin. 28 (10), 2411-2417 (2012).

6. Iskra Staneva, Yongqi Huang, Zhirong Liu, and Stefan Wallin. Binding of two intrinsically disordered peptides to a multi-specific protein: a combined Monte Carlo and molecular dynamics study. PLoS Comput. Biol. 8 (9), e1002682/1-9 (2012).

7. Yongqi Huang, Huaiqing Cao, and Zhirong Liu. Three-dimensional domain swapping in the protein structure space. Proteins: Struct. Funct. Bioinform. 80 (6), 1610-1619 (2012).

8. Yongqi Huang and Zhirong Liu. Anchoring intrinsically disordered proteins to multiple targets: lessons from N-terminus of the p53 protein. Int. J. Mol. Sci. 12 (2), 1410-1430 (2011).

9. Yongqi Huang and Zhirong Liu. Nonnative interactions in coupled folding and binding processes of intrinsically disordered proteins. PLoS ONE 5 (11), e15375/1-10 (2010).

10. Yongqi Huang and Zhirong Liu. Smoothing molecular interactions: the "kinetic buffer" effect of intrinsically disordered proteins. Proteins: Struct. Funct. Bioinform. 78 (16), 3251-3259 (2010).

11. 黃永棋、劉志榮。天然無序蛋白質: 序列-結構-功能的新關系。 物理化學學報 26 (8), 2061-2072 (2010).
Yongqi Huang and Zhirong Liu. Intrinsically disordered proteins: the new sequence-structure-function relations. Acta Phys. -Chim. Sin.26 (8), 2061-2072 (2010).

12. Yifei Qi*, Yongqi Huang*, Huanhuan Liang, Zhirong Liu, and Luhua Lai. Folding simulations of a de novo designed protein with a βαβ fold. Biophys. J. 98 (2), 321-329 (2010).

13. Yongqi Huang and Zhirong Liu. Kinetic advantage of intrinsically disordered proteins in coupled folding-binding process: a critical assessment of the "fly-casting" mechanism. J. Mol. Biol. 393 (5), 1143-1159 (2009). [422 (1), 156 (2012).]

14. Yongqi Huang, Huifang Li, and Yuxiang Bu. Molecular dynamics simulation exploration of cooperative migration mechanism of calcium ions in sarcoplasmic reticulum Ca2+-ATPase. J. Comput. Chem. 30 (13), 2136-2145 (2009).

 

參加會議：

1. Yongqi Huang, Nonnative Interactions in Coupled Folding and Binding Processes of Intrinsically Disordered Proteins. Poster. Barcelona BioMed Conference on "Intrinsically disordered proteins in biomedicine", Barcelona, Spain. October 4-6, 2010.

2. Yongqi Huang and Zhirong Liu, Nonnative Interactions in the Binding Process of Intrinsically Disordered Proteins: Implication for Interaction Promiscuity and Aggregation. Poster + short talk. The 3rd Asia Pacific Protein Association (APPA) Conference（第三屆亞太地區蛋白質科學大會）, Shanghai University, Shanghai, China. May 6-9, 2011.

3. Yongqi Huang, Xue Kang, Bin Xia, and Zhirong Liu, Unfolding simulation of C-terminal domain of SARS-CoV main protease: the swapping core helix. Poster. The 25th Anniversary Symposium of the Protein Society, Boston, Massachusetts, U.S.A., July 23-27, 2011.

 

獲獎情況:

1. 2009、2010、2011年，定量生物學中心獎學金二等獎

2. 2009年，beat365蘇州工業園區獎學金

3. 2010年，beat365東港獎學金

4. 2011年，beat365鐘陳玉蘭獎三等獎學金

5. 2011年，Finn Wold Travel Award, The Protein Society, 美國

6. 2012年，beat365化學學院2012年優秀博士學位論文