beat365

 

  夏斌
職務:教育部“長江學者獎勵計劃”特聘教授 
北京核磁共振中心主任兼首席科學家
beat365官方网站分析化學專業博士生導師
beat365生命科學學院生物化學與分子生物學專業博士生導師
個人簡曆: 1989年畢業于beat365生物系 獲學士學位
  1997年在美國University of Wisconsin-Madison
獲博士學位
  1997年至2001年在美國The Scripps Research Institute
博士後
     
聯系方式: Tel: 010-62758127
Fax:010-62753790
E-mail: binxia@pku.edu.cn
 
     
研究興趣: 蛋白質結構與功能關系的核磁共振譜學研究
蛋白質的結構基因組學研究
疾病的代謝組學研究
 


2005年以來主要代表文獻:

  1. C-terminal domain of SARS-CoV main protease can form a 3D domain-swapped dimer. Zhong N, Zhang S, Xue F, Kang X, Zou P, Chen J, Liang C, Rao Z, Jin C, Lou Z, Xia B. Protein Sci. 2009 Apr;18(4):839-44. PMID: 19319935
  2. Automics: an integrated platform for NMR-based metabonomics spectral processing and data analysis. Wang T, Shao K, Chu Q, Ren Y, Mu Y, Qu L, He J, Jin C, Xia B. BMC Bioinformatics. 2009 Mar 16;10:83. PMID: 19291281
  3. A novel Bcl-XL inhibitor Z36 that induces autophagic cell death in Hela cells.
    Lin J, Zheng Z, Li Y, Yu W, Zhong W, Tian S, Zhao F, Ren X, Xiao J, Wang N, Liu S, Wang L, Sheng F, Chen Y, Jin C, Li S, Xia B. Autophagy. 2009 Apr;5(3):314-20. Epub 2009 Apr 16. PMID: 19242113
  4. Solution structure of human zeta-COP: direct evidences for structural similarity between COP I and clathrin-adaptor coats. Yu W, Lin J, Jin C, Xia B. J Mol Biol. 2009 Mar 6;386(4):903-12. PMID: 19167404
  5. Solution structure of GSP13 from Bacillus subtilis exhibits an S1 domain related to cold shock proteins. Yu W, Hu J, Yu B, Xia W, Jin C, Xia B. J Biomol NMR. 2009 Apr;43(4):255-9. PMID: 19152054
  6. Solution structure and catalytic mechanism of human protein histidine phosphatase 1. Gong W, Li Y, Cui G, Hu J, Fang H, Jin C, Xia B. Biochem J. 2009 Mar 1;418(2):337-44. PMID: 18991813
  7. Without its N-finger, the main protease of severe acute respiratory syndrome coronavirus can form a novel dimer through its C-terminal domain. Zhong N, Zhang S, Zou P, Chen J, Kang X, Li Z, Liang C, Jin C, Xia B. J Virol. 2008 May;82(9):4227-34. Epub 2008 Feb 27. PMID: 18305043
  8. 1H, 13C, and 15N resonance assignments of human ζ-COP. Wenyu Yu, Changwen Jin and Bin Xia (2008) Biomolecular NMR Assignments 2008 2:73–75.
  9. 1H, 13C, and 15N resonance assignments of a general stress protein GSP13 from Bacillus subtilis. Wenyu Yu, Bingke Yu, Jicheng Hu, Wei Xia, Changwen Jin, Bin Xia (2008) Biomolecular NMR Assignments 2008 2:163–165
  10. 1H, 13C, and 15N resonance assignments of human phosphohistidine phosphatase 1 (PHPT1)Weibin , Gaofeng Cui, Changwen Jin and Bin Xia Biomolecular NMR Assignments 2007 1:229-231
  11. Gossypol induces Bax/Bak-independent activation of apoptosis and cytochrome c release via a conformational change in Bcl-2. Lei X, Chen Y, Du G, Yu W, Wang X, Qu H, Xia B, He H, Mao J, Zong W, Liao X, Mehrpour M, Hao X, Chen Q. FASEB J. 2006 Oct;20(12):2147-9. Epub 2006 Aug 25. PMID: 16935937
  12. Structural insight into poplar glutaredoxin C1 with a bridging iron-sulfur cluster at the active site. Feng Y, Zhong N, Rouhier N, Hase T, Kusunoki M, Jacquot JP, Jin C, Xia B. Biochemistry. 2006 Jul 4;45(26):7998-8008. PMID: 16800625
  13. Identification and solution structures of a single domain biotin/lipoyl attachment protein from Bacillus subtilis. Cui G, Nan B, Hu J, Wang Y, Jin C, Xia B. J Biol Chem. 2006 Jul 21;281(29):20598-607. Epub 2006 May 14. PMID: 16699181
  14. Periplasmic protein HdeA exhibits chaperone-like activity exclusively within stomach pH range by transforming into disordered conformation. Hong W, Jiao W, Hu J, Zhang J, Liu C, Fu X, Shen D, Xia B, Chang Z. J Biol Chem. 2005 Jul 22;280(29):27029-34. Epub 2005 May 23. PMID: 15911614
  15. 1H, 15N, and 13C resonance assignments of reduced glutaredoxin C1 from Populus tremula x tremuloides. Feng Y, Rouhier N, Jacquot JP, Xia B. J Biomol NMR. 2005 Mar;31(3):263-4. No abstract available. PMID: 15803403
  16. 1H, 13C, and 15N resonance assignments of the N-terminal domain of the SARS CoV nucleocapsid protein. Zhong N, Huang Q, Jin C, Xia B. J Biomol NMR. 2005 Jan;31(1):79-80. No abstract available. PMID: 15692748
     
[夏斌教授課題組] [核磁中心首頁]
 

 

教師ftp
在線辦公
TOP