Research News, Jan 6, 2010
研究室工作進展 January 6, 2010
Isolation and X-ray Structure of a Trimeric 1,4-Dilithio-1, 3-butadiene and a Dimeric Me3Si-substituted 1,4-dilithio-1,3-butadiene
Lantao Liu, Wen-Xiong Zhang,* Qian Luo, Heng Li, and Zhenfeng Xi*
Organometallics 2010, 29, 278-281.
The X-ray crystallographic structures of a trimeric all-alkyl substituted 1,4-dilithio-1,3- butadiene with a Li6 pseudooctahedron as well as of the dimeric Me3Si-substituted 1,4-dilithio-1,3-butadiene with a Li4 tetrahedron are reported.
本工作背景介紹
本研究小組自1999年發現1,4-雙锂-1,3-丁二烯衍生物具有不同與常見單锂金屬有機合成試劑的反應模式以來，一直努力建立合成該類衍生物純品的有效方法，以便最終将這類衍生物發展成方便使用的雙锂金屬有機合成試劑；同時，我們希望了解該類雙锂金屬有機化合物尤其是全烷基取代的衍生物的結構與成鍵模式。經過幾代研究生的努力，最終在2009年由劉瀾濤同學在張文雄老師的指導下完成該工作，可以方便地以80%以上的分離收率獲得克級以上多種衍生物的晶體（其中之一如圖），并作為試劑方便地用于進一步的反應。
Background of this work
1,4-Dilithio-1,3-butadienes found by our group in 1999 demonstrate different reaction patterns from commonly widely used mono-Li reagents. Since then, we have tried to establish an efficient synthetic method to get pure compounds, aiming at developing such compounds as useful organo-di-lithio reagents. After many trials by several graduate students, this goal was finally achieved in 2009 by Mr. Lantao Liu and Dr. Wen-Xiong Zhang. Most of such derivatives now can be obtained in this group as fine crystalline compounds in over 80% isolated yields with gram-scale. The picture shows one of such derivatives, which are kept in cooler and used when needed.