報告人: Prof. Jin-Quan Yu

            Department of Chemistry

            The Scripps Research Institute

時　間: 2018年9月14日(星期五)下午3:30

地　點: 化學樓A204/206

邀請人: 雷曉光

Enantioselective and Remote C–H Activation Reactions

Inspired by how enzymes use directing effect to achieve remote selective C–H activation, we have developed a number of site-selective remote C–H activation reactions which are fundamentally distinct from the classic directed C–H activation via cyclometalation processes. We focused our design on recognition of distance and geometry as the simplest parameters to achieve site selectivity, which has allowed us to enantio-selectively activate C–H bonds at remote sites, that are previously not accessible. The combination of remote directing effect and ligand acceleration is analogous to flying a kite in the wind.

歡迎參加！